NONI Magical plant Following the words of the famous Persian physician-scientist Avicenna and using modern achievements of science, we can say that this is enough to ensure the proper functioning of the cells of the human body to enjoy good health.
This means that only fully nourished cells can regenerate to function properly and efficiently. The cell also needs to be given the ability to produce energy. A cell that does not produce energy dies.
These processes take place in the mitochondria, which also require an adequate “supply” of nutrients.
Modern food not only does not provide us with the necessary nutrients, but it can be contaminated with antibiotics, pesticides and toxic chemicals.
A stressful lifestyle, constant tension, lack of physical activity, exposure to media fear-inducing reports, uncritical submission to advertising, etc. only worsen our health. Of course, to the extent that we are aware, we try to take care of our health, but I believe that it is often a “fight with windmills” because we cannot separate ourselves from civilization, so to speak, and live outside of it.
What is noni made of?
WHAT IS NONI MADE OF? Noni (Morinda Citrifolia L.) is a nutritious whole food. Approximately 200 phytochemicals have been identified and isolated from different parts of the noni plant. To date, several classes of metabolites have been described in different parts of the plant, including acids, alcohols and phenols, anthraquinones, anthraquinone glycosides, carotenoids, esters, flavonoids, iridoids, ketones, lactones, lignans, nucleoids, triterpenoids, triterpenoids, and several smaller compounds. Also noteworthy is the occurrence of scopoletin (coumarin), a metabolite that occurs in several plant families. This coumarin is relevant because its promising biological drug activities have been reported, such as: antiangiogenic, hepatoprotective, antioxidant, spasmolytic, and antiproliferative in human prostate cancer. In addition, we should highlight the anthraquinone damnacanthal, which appears in nona and other species from family Rubiaceae. This substance is particularly interesting because of its antitumor properties potential.
Phytochemicals isolated from Morinda citrifolia L. Acids Triterpenoids and sterols Alcohols and phenols. Triterpenoids and sterols Anthraquinones Various compounds, for example Esters Vitamins: C, B1, B2, B6, B12, Flavonoids folic acid, biotin, niacin, Iridoids pantothenic acid, E, arotene Ketones Minerals – iron, phosphorus, Lactones magnesium, calcium, molybdenum, Lignan sodium, potassium, manganese, chromium Nucleoids 18 amino acids Saccharides, polysaccharides
Fermented Noni juice is superior in terms of popularity, acceptability, according to therapists reports. The noni plant and its derivatives have shown potent therapeutic properties against inflammation, infection, hypertension, cancer, ulcers, constipation, and autoimmune diseases.
Over the past few decades, many bioactive compounds have been structurally identified and elucidated from many parts of the plant. The phytochemical profiling of the fruit of Morinda Citrifolia L. is well established and elucidated.
The rich composition of noni and, most importantly, the synergistic action of individual components enables a wide range of therapeutic applications.
THERAPEUTIC ACTION OF NONI
The noni plant exhibits an exceptionally high therapeutic and safety profile, making it popular as a health enhancer and dietary supplement worldwide.
Morinda citrifolia (noni) is used for more than 40 types of diseases worldwide.
The use of noni as a medicinal plant and its bioactivity have long been studied by ethnobotanists. Traditional Polynesian medicine has used noni for over 2000 years to treat headaches, fever, arthritis, gingivitis, respiratory disorders, infections, tuberculosis, diabetes, central nervous system disorders.
Noni fruit juice is used in the Pacific region for the treatment of cancer and is believed to have analgesic, anti-inflammatory, antioxidant, detoxifying and cell rejuvenating properties [5].
Publications demonstrate that noni is pharmacologically active and is used in various forms of cancer, e.g. colon, esophageal, breast, colorectal cancer; cardiovascular diseases, diabetes, arthritis, hypertension. These properties are supported by preclinical and/or clinical studies [6].
The following sections will present possible therapeutic applications of noni juice
ANTIOXIDATIVE ACTION
Antioxidant compounds are compounds that can inhibit free radicals. Many degenerative human diseases are recognized as a consequence of free radical damage. Studies have shown that high consumption of fruits and vegetables containing phenolic antioxidants, inhibits the oxidation of low-density lipoprotein (LDL), thus slowing down the process of atherosclerosis and reducing the risk of cancer and many other diseases. It is encouraging to see that all chromatographic fractions obtained from the roots, fruit and leaves of the noni plant have shown high antioxidant activity [1]. Studies have shown that treatment with Noni juice significantly increases the levels of antioxidant enzymes such as catalase, SOD. Noni juice has also shown a preventive effect against anemia, lymphocytosis and neutrophilia [6]. Noni has anti-inflammatory potential, significantly reducing leukocyte migration and can be used as an alternative against pain and inflammatory conditions, including those associated with oxidation
ANTI-INFLAMMATORY AND ANALGESIC ACTIVITY
Noni’s strong anti-inflammatory activity and its cancer prevention mechanisms have been reported (for anticancer activity, see the following chapters).
Studies of the anti-inflammatory properties of noni have shown that the selectivity of COX-2 (enzyme involved in the formation of the factor responsible for pain and inflammation) – inhibition of noni comparable to that Celebrex (a non-steroidal drug with anti-inflammatory and analgesic effects) [4].
The results presented in the studies show that noni fruit can reduce the key inflammatory cytokines that are also involved in the development of intestinal inflammation.
Anti-inflammatory effects have been found to be regulated by many factors.
The findings reveal the mechanisms underlying the anti-inflammatory action of noni fruit compounds and their potential therapeutic use against inflammation-related disorders. Five compounds, particularly active in anti-inflammatory action, were isolated, for example, rutin, asperulosidic acid, other iridoids.
Researchers have claimed that noni fruit has analgesic and relaxing effects. Noni pointed significant dose-dependent central analgesic activity. They reported that “these results confirm the traditional analgesic properties of this plant”. Analgesic power of noni is about 75% of morphine, but it does not cause addiction and has no unwanted effects.
The ingredients found in the Noni fruit have anti-inflammatory and analgesic effects. Using min. 60 ml of Noni juice per day you will feel a noticeable relief from yours hardship.
ANTIMICROBIAL ACTIVITY
Noni also exhibits antimicrobial activity. This is an extremely important property because we live in an environment that can be threatened by various pathogens.
The antimicrobial activity of Noni was evaluated in cells in vitro on Escherichia coli, Candida albicans and Staphylococcus aureus. Candida albicans was the most sensitive to Noni antimicrobial activity. This activity is associated with a high iridoid content in the fruit, especially deacetylasperulosidic acid and asperulosidic acid.
Ripe and unripe Noni fruits can be used for the treatment and prevention of gastroenteritis and pyrogenic infections caused by human pathogenic bacteria.
The researchers noted that scopoletin, a health-promoting compound obtained from the fruit Nonia inhibits the activity of Escherichia coli. They further pointed out that Noni inhibited Helicobacter pylori, the activity of bacteria that cause stomach ulcers.
The compounds of Noni have a great ability to fight against the infectious diseases they cause bacterial strains such as Pseudomonas aeruginosa, Proteus morgaii, Staphilococcus aureus, Bacillis subtilis, E. coli, Salmonella and Shigella.
Other researchers have reported that the antibacterial ingredients of Noni are responsible for the healing of skin infections diseases, colds, fevers and other health problems caused by bacteria [9]. We now see the importance of this small fruit due to its wide range of therapeutic potentials such as antimicrobial effects.
Consuming 60 ml of Noni fruit juice daily can help reduce the activity of pathogenic bacteria.
